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Labcorp is a leading global life sciences company that includes contract research and developmental services to thepharmaceutical,medical technology,crop protectionandchemicalindustries.
Covance Is Now Labcorp Drug Development
We are one global company innovating for millions – together, continuing to bring you more advanced medical breakthroughs.
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A collection of nonclinical studies & assays; customization is possible.
Pyloric ligation procedure
Pyloric ligation procedure
Pyloric ligations induce accumulation of acid and pepsin, which leads to autodigestion of gastric mucosa and ulceration. Some studies administer pentagastrin or histamine dihydrochloride subcutaneously.
After the stomach content is collected, the volume of gastric juice is recorded and the concentration of free acid can be calculated and analyzed.
About our nonclinical animal research models: We provide the utmost care for our research animals and actively pursue advances in animal welfare. As well as ensuring the highest scientific, ethical and regulatory standards, selection of appropriate animal research models for development research is critical to developing safe and effective treatments, devices and products that protect and save lives. Just as we have ethical committee oversight for human trials, we have ethical committees overseeing all aspects of our global animal care and use programs. All of our core, nonclinical facilities are accredited by AAALAC.Learn more about our commitment to replacing, reusing and refining nonclinical research models.